Since metabolic conversion of lactate to bicarbonate is dependent on the integrity of cellular oxidative processes, lactate may be inadequate or ineffective as a source of bicarbonate in patients suffering from acidosis associated with shock or other disorders involving reduced perfusion of body tissues. It is derived from natural L(+) lactic acid, a weak acid having a dissociation 86 constant of 1.389.10-4 at 22°C (pKa=3.857).Sodium lactate has a content of 59-61% (w/w) and a It occurs naturally in the skin as part of the skinâs NMF (Natural Moisturizing Factors), and is an excellent humectant. Jungbunzlauer sodium L (+)-lactate/sodium diacetate is a colourless to yellowish, syrupy liquid with a slight characteristic odour and a saline taste. It should not be used in conditions in which lactate levels are increased (e.g., shock, congestive heart failure, respiratory alkalosis) or in which utilization of lactate is diminished (e.g., anoxia, beriberi). All or part of the content(s) of one (50 mEq in 10 mL) or more vial containers may be added to other intravenous solutions to provide any desired number of milliequivalents of lactate anion (with the same number of milliequivalents of Na+). It is seldom measured as such and thus is one of the "unmeasured anions" ("anion gap") in determinations of the ionic composition of plasma. FOR INTRAVENOUS USE. Sodium Lactate. It is not known whether this drug is excreted in human milk. Sodium lactate hardens cold process soap so you can unmold and enjoy it more quickly. Sodium Lactate CAS Number 72-17-3 or 867-56-1, EINECS EC Number 200-772-0, HS Code ---**; Molecular Weight 112.06, Molecular Formula: C 3 H 5 NaO 3. The contents of one container (50 mEq in 10 mL) added to 290 mL of a nonelectrolyte solution or of sterile water for injection will provide 300 mL of an approximately isotonic (1/6 molar) concentration of Sodium Lactate (1.9%), containing 167 mEq/liter each of Na+ and lactate anion. Sodium Lactate. The recommended amount to use is about 1 ⦠PROPANOIC ACID, 2-HYDROXY-,MONOSODIUM SALT Propanoic Acid, 2-Hydroxy-, Monosodium Salt. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is supplied in 10 mL single-dose plastic vials. Discard unused portion. See CONTRAINDICATIONS. Ultralac SL -60 (Sodium Lactate 60%) General Characteristics: Appearance: Clear, colorless liquid. Acetazolamide is a mild ⦠The lactate anion is in equilibrium with pyruvate and has an alkalizing effect resulting from simultaneous removal by the liver of lactate and hydrogen ions. In the event of overdosage, discontinue infusion containing Sodium Lactate immediately and institute corrective therapy as indicated to reduce elevated serum sodium levels and restore acid-base balance if necessary. An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. It should not be administered undiluted. Available for Android and iOS devices. This solution is stable under normal storage conditions, non-toxic to humans and the environment and readily biodegradable. PubChem Substance ID 24896392. �A~�L>&G. The amount of sodium ion and lactate ion to be added to larger volume intravenous fluids should be determined in accordance with the electrolyte requirements of each individual patient. It is also not known whether Sodium Lactate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. The lactate in Compound Sodium Lactate solution is metabolized by both oxidation and gluconeogenesis, predominantly in the liver, and bicarbonate is generated by both processes over 1-2 h. When medication is added to Compound Sodium Lactate Solution, the overall pharmacokinetics of the solution will depend on the nature of the drug used. pregnancy, upcoming surgery, etc. Section 1: Chemical Product Identification Page 1 of 6 Sodium Lactate 60% Solution CAS No 72-17-3 MATERIAL SAFETY DATA SHEET SDS/MSDS . CAUTION: MUST BE DILUTED. ], Distributed by Hospira, INC., Lake Forest, IL 60045 USA. ), allergies, pre-existing diseases, and current health conditions (e.g. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. It is a significantly stronger humectant than vegetable glycerin, with over twice the water holding capability. Buy Sodium Lactate at BrambleBerry. 80 Sodium Lactate 81 The structural formula for sodium lactate is: 82 83 Figure 2: The structural formula of sodium lactate 84 85 Sodium lactate is hygroscopic. [See USP Controlled Room Temperature. The safety and effectiveness of Sodium Lactate have not been established in pediatric patients. Sodium Lactate Powder. The sodium salt of lactic acid.It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. An organic sodium salt having lactate as the counterion. Sodium Acetate Anhydrous is the anhydrous, sodium salt form of acetic acid.Sodium acetate anhydrous disassociates in water to form sodium ions (Na+) and acetate ions. In the liver, lactate is metabolized to glycogen which is ultimately converted to carbon dioxide and water by oxidative metabolism. Sodium Lactate 50% demonstrates its water-retention effect even under conditions of low temperature and low humidity. See WARNINGS and PRECAUTIONS. Molecular formula. Medically reviewed by Drugs.com. Before using Sodium Lactate, inform your doctor about your current list of medications, over the counter products (e.g. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. It comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter. Bacteriostatic effect of Sodium Lactate 50%. The container requires no vapor barrier to maintain the proper drug concentration. Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing "raw material" for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a result of disordered lactate metabolism. Studies with Sodium Lactate Injection have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. chemBlink provides information about CAS # 72-17-3, Sodium lactate, Sodium DL-lactate, Lactic acid sodium salt, (+/-)-2-Hydroxypropionic acid sodium salt, molecular formula: C3H5NaO3. CAS names . Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. Sodium Lactate injection, solution, concentrate, We comply with the HONcode standard for trustworthy health information -, ANALYSIS(0409-6664), LABEL(0409-6664), MANUFACTURE(0409-6664), PACK(0409-6664). Uses of Sodium Lactate: It is used to treat or prevent acid problems in the blood. Select one or more newsletters to continue. Sodium lactate in plastic container . Molecular Formula C 3 H 5 NaO 3; Average mass 112.060 Da; Monoisotopic mass 112.013641 Da; ChemSpider ID 6049 - Charge. You need this product in your collection. Sodium 2-hydroxyprop anoate. The usage rate for sodium lactate is 1 tsp. Below are two batches of ⦠Lactate is one of the main components of Ringerâ²s lactate⦠CAS Number. �`z�O�ﾼ�/_�G!&���Z::��y np֬�9�Up���5�Ԝ���(e�H�x/.�l}���6���A�G8W4��_���X��s|���o�3�|��f�`@!P1��e�n�{�����6��_��r�/�����)��[�$�r%�1�\�7,�a�8A��*Ha5��!+��v����-X��t��"�6�U�\R��]�m��4L���SPg�A��a� �=7d ��x^�ɰ袯yN�;�p�� ��,� )o�����(��ȑx�y3�4����BϦE�i�46�qp0�>NyX_l|�)�k����.�ح�.�M�z9OS��| �x�� ����Lػ��6+�Wq��W�DKY��l Animal reproduction studies have not been conducted with Sodium Lactate. SECTION 4: First aid ⦠Sodium is the principal cation of extracellular fluid. The sodium (Na+) ion combines with bicarbonate ion produced from carbon dioxide of the body and thus retains bicarbonate to combat metabolic acidosis (bicarbonate deficiency). Beilstein/REAXYS Number 4567087 . If you have an allergy to sodium lactate or any other part of sodium lactate. In the soap making process, sodium lactate is added to the lye/water solution once the temperature is below 54 degrees Celsius. SMILES. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. Simply measure out the sodium lactate, and stir into the cool lye water. This solution is stable under normal storage conditions. The potentially large loads of sodium given with lactate require that caution be exercised in patients with congestive heart failure or other edematous or sodium-retaining states, as well as in patients with oliguria or anuria. CAUTION: MUST BE DILUTED. EC Number 212-762-3. MDL number MFCD00066576. Buy Sodium L-lactate (CAS 867-56-1), a simple 3 carbon sugar produced from pyruvate via LDH in mammals, from Santa Cruz. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You can also use it in lotion to draw moisture to the skin, or in hot process soap to make it more fluid and smooth. Contains hydrochloric acid for pH adjustment. Sodium lactate 1/6 molar in plastic container . : 72-17-3 General description: Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Sodium Lactate is a sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. Its limited use has been inadequate to fully define proper dosage and limitations for use. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is administered intravenously only after addition to a larger volume of fluid. Our team of experts are at the ready. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Sodium lactate powder is the solid sodium salt of natural L-Lactic acid, Sodium lactate powder 98 is a white powder. Product Information. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. The normal plasma level of lactate ranges from 0.9 to 1.9 mEq/liter. The semi-rigid vial is fabricated from a specially formulated polyolefin. About Sodium Lactate Enquire Now. Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt, Sodium L-lactate Empirical Formula (Hill Notation): C 3 H 5 NaO 3 Molecular Weight: 112.06 Other . It's a liquid salt derived from the fermentation of sugars found in corn and beets. When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3). Sodium Lactate SDS, Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 05-Dec-20. Sodium Lactate is the natural salt derived from a natural fermentation product, lactic acid. Sodium L-lactate ~98% Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt CAS Number 867-56-1. Dist. by Hospira, Inc., Lake Forest, IL 60045 USA, NDC 0409-6664-02 It's a natural ingredient approved by both ECOCERT and COSMOS. The solution contains no bacteriostat, antimicrobial agent or added buffer. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. Demonstrates an anti-drying effect in various foods, particularly delicacies and confectioneries. Sodium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Sodium Lactate. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. CHF, shock, respiratory alkalosis or other conditions that increase lactate. Do not administer unless solution is clear and seal is intact. Last updated on Dec 1, 2019. Sodium lactate is non-toxic to humans and the environment and is readily biodegradable. See WARNINGS and PRECAUTIONS. The sodium ion exerts a primary role in controlling total body water and its distribution. Dosage Form: injection, solution, concentrate. More details: Systematic name. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate ⦠Sodium Lactate should be given to a pregnant woman only if clearly needed. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Avoid rapid administration and overdosage. Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions, to patients receiving corticosteroids or corticotropin. Formula : C3H5NaO3 Molecular Weight : 112,06 g/mol No components need to be disclosed according to the applicable regulations. Empirical Formula (Hill Notation) C 3 H 5 NaO 3. Store at 20 to 25°C (68 to 77°F). Sodium Lactate is one of the Natural Moisturizing Factor (NMF) constituent of skin, required in the maintenance of natural hydration. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. vitamins, herbal supplements, etc. It is naturally produced in the skin, according to an article published in Cosmetics and Toiletries, and also occurs naturally in all animal and human muscle tissue, according to Sodium-Lactate.com. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. per pound of oils. Safety Data Sheets Download. Jungbunzlauer sodium L (+)-lactate is a colourless to yellowish, nearly odourless aqueous solution with a mild salty taste. It should not be administered undiluted. The intravenous administration of this solution (after appropriate dilution) can cause fluid and/or solute overloading resulting in dilution of other serum electrolyte concentrations, overhydration, congested states or pulmonary edema. Email: info@alfa-chemistry.com Tel:1-201-478-8534 1-516-662-5404 Fax: 1-516-927-0118 Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA For product inquiries, please use our online system or send an email to inquiry@alfa-chemistry.com Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion). It is a copolymer of ethylene and propylene. The osmolar concentration is 10 mOsmol/mL (calc.). Be careful not to use too much; using too much sodium lactate will result in a hard, crumbly bar of soap. Molar mass of NaC3H5O3 = 112.05977 g/mol Convert grams Sodium Lactate to moles or moles Sodium Lactate to grams. China Sodium Lactate manufacturers - Select 2020 high quality Sodium Lactate products in best price from certified Chinese High Pressure Sodium manufacturers, Sodium Phosphate suppliers, wholesalers and factory on Made-in-China.com Sodium Lactate, a 60% concentration in water, and is the sodium salt of natural L(+)-Lactic Acid, produced through the fermentation of sugar, an alpha hydroxy acid that occurs everywhere in nature. Sodium Lactate 60% â Food Grade. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. Isotonic saline infusion can be used to expand the extracellular fluid volume, and it is also acidifying. Sodium lactate and NH4Cl should not be administered to patients with liver disease. Cautions. Sodium Lactate Injection, USP 50 mEq must be suitably diluted before infusion to avoid a sudden increase in the level of sodium or lactate. For Intravenous Use. Sodium Lactate and Soap. Significant hypokalemia may occur. Sodium Lactate. It is a free flowing hygroscopic salt and has a neutral pH.-Chemical name: Sodium lactate powder-Standard: Food grade FCC-Appearance: crystalline powder-Color: white color-Odor: odorless Too rapid administration and overdosage should be avoided. Sodium Lactate Injection, USP 50 mEq is contraindicated in patients suffering from hypernatremia or fluid retention. Sodium Lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis. Molecular Weight 112.06 . Additive Number. â¦sodium salt Formula: CH 3 CH(OH)COONa Formula Weight: 112.06 CAS No. Sodium lactate solution is a natural food additive, it is used as water retention agent, antioxidant synergists, emulsifiers, also can be used as pH adjusting agents (e.g. Sodium lactate (sodium lactate injection in aviva) is chemically designated as propanoic acid, 2-hydroxy-,monosodium salt and has the following structural formula: CH 3 CH (OH)COONa C 3 H 5 NaO 3 112.1 A 60% aqueous solution is miscible in water. Sodium lactate is used in soap making to produce a harder long lasting bar of soap. Only and is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate.... Particularly delicacies and confectioneries be given to a nursing mother Forest, IL 60045 USA..! Overdosage of either sodium or Lactate ions should be used with caution excess. Formula ( Hill Notation ) C 3 H 5 NaO 3 ; mass... 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Injection is administered after dilution by the intravenous route as an electrolyte and... Mammals, from Santa Cruz is supplied in 10 mL vial contains sodium Lactate and NH4Cl not! Plasma concentration of approximately 140 mEq/liter approximately 140 mEq/liter I take sodium Lactate has advantage! 1 tsp define proper dosage and limitations for use dehydrogenase ( LDH.. Sugar produced from pyruvate by the ChEBI Team and updates limited use has been manually annotated by the Team. And readily biodegradable of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property a stronger! Miscible in water ) sodium lactate formula health conditions ( e.g sodium retention required conversion! In various foods, particularly delicacies and confectioneries inspected visually for particulate matter and discoloration prior to.! C 3 H 5 NaO 3 ; Average mass 112.060 Da ; ID. Not been established in pediatric patients salt derived from the fermentation of sugars found in corn and.! A liquid salt derived from the fermentation of sugars found in corn and beets conversion of Lactate to or! Your own personal medication records or fluid retention... an organic sodium of. Differences in response between elderly and younger patients potential, mutagenic potential or effects on fertility ingredient!
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